It is tempting at first to follow anyone you come across, but that strategy can quickly backfire. I would recommend following only people who are worth following, these don’t have to be people you know personally, but they should meet the following criteria:
✓ when looking back on their posts, make sure they are of quality and content you would like to read in the future
✓ they are respectable individuals, you don’t want to follow sleazy sales, haters, vulgar, or otherwise obnoxious people
✓ follow trend-setters in your area of interest, you want to be the first informed person who “finds” and re-tweet some groundbreaking news
✓ key people to whom our post may provide value
✓ if you are attending a conference follow all participants, you never know who you are going to meet, a week after the conference you can do some cleaning up